Andrew Luck
We will always have the memory of Luck, being one of the most talented quarterbacks to play in the league. During his career, he suffered a lower-body injury, which leads to his desire to retire from the sport during the preseason. He played six years for the Colts but never returned.
Andrew Luck
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Gale Sayers
The legendary player Gale Sayers had to end his career early, after suffering from knee injuries. He spent seven seasons with the Chicago Bears and was placed into the Pro Football Hall of Fame when he was 34.
Gale Sayers
